Can the RTX 4080 Super 16 GB run Wan 2.2 S2V 14B?
Download Q2_K (9.5 GB). With the model's working memory it needs about 14.3 GB, leaving 1.7 GB spare on 16 GB. Quality: heavy loss; a last resort. For better quality, Q3_K_M (11.4 GB) also runs, with about 0.2 GB spilling into system RAM — a little slower, still practical.
Worth trying on this GPU: with an up-to-date ComfyUI, Dynamic VRAM (on by default for NVIDIA since March 2026) streams whatever does not fit from system RAM, and ComfyUI's own start-up message recommends native FP8/INT8 files over GGUF, saying they “will be faster even if they are larger than your memory”. So before settling for a heavily compressed GGUF, try the native FP8 file (16.4 GB). The file recommended above is the best one that fits entirely — the safe choice on older ComfyUI versions, AMD and Intel. Comfy blog: Dynamic VRAM →
01What to download
| Part | File | Folder | Size | |
|---|---|---|---|---|
| Model | Wan2.2-S2V-14B-Q2_K.gguf Q2_K · QuantStack/Wan2.2-S2V-14B-GGUF | models/unet | 9.5 GB | Download → |
| Text encoder | umt5_xxl_fp8_e4m3fn_scaled.safetensors UMT5-XXL FP8 (scaled) · Comfy-Org/Wan_2.1_ComfyUI_repackaged | models/text_encoders | 6.7 GB | Download → |
| VAE | wan_2.1_vae.safetensors Wan 2.1 VAE · Comfy-Org/Wan_2.2_ComfyUI_Repackaged | models/vae | 0.3 GB | Download → |
| Also needed | wav2vec2_large_english_fp16.safetensors wav2vec2 large English FP16 (audio encoder) · Comfy-Org/Wan_2.2_ComfyUI_Repackaged | models/audio_encoders | 0.6 GB | Download → |
| Total download · keep about the same free on disk | 17.1 GB | |||
Alternatives: UMT5-XXL FP16 (11.4 GB). The 16-bit text encoder is a little more faithful; the smaller one is chosen here because it loads faster and needs less RAM. Sizes read from Hugging Face (2026-09-25). “Download” links start the file directly; the file name links are the same files the official ComfyUI workflows use.
System RAM: 32 GB or more. ComfyUI keeps the model file, the text encoder and the VAE in system RAM and moves them to the GPU as needed. With this set of files that is about 17.1 GB, plus roughly 6 GB for Windows, ComfyUI and a browser: 23.1 GB in total. With less RAM it still runs, but Windows starts swapping to disk and loading gets very slow. calculated
02Every Wan 2.2 S2V file on 16 GB
| File | Size | Needed | On this card | Quality | Download |
|---|---|---|---|---|---|
| 16-bit SAFETENSORS · Comfy-Org | 32.6 GB | 37.4 GB | 21.4 GB too big | the original weights | Hugging Face → |
| FP8 SAFETENSORS · Comfy-Org | 16.4 GB | 21.2 GB | 5.2 GB too big | practically identical to the original | Hugging Face → |
| Q8_0 GGUF · QuantStack | 19.6 GB | 24.4 GB | 8.4 GB too big | practically identical to the original | Hugging Face → |
| Q6_K GGUF · QuantStack | 16.2 GB | 21.0 GB | 5.0 GB too big | very close to the original | Hugging Face → |
| Q5_K_M GGUF · QuantStack | 15.0 GB | 19.8 GB | 3.8 GB too big | close; small differences in fine detail | Hugging Face → |
| Q4_K_M GGUF · QuantStack | 13.9 GB | 18.7 GB | 2.7 GB too big | good; some loss in fine detail and text | Hugging Face → |
| Q3_K_M GGUF · QuantStack | 11.4 GB | 16.2 GB | spills 0.2 GB | noticeable loss of detail | Hugging Face → |
| Q2_K ← GGUF · QuantStack | 9.5 GB | 14.3 GB | fits · 1.7 GB spare | heavy loss; a last resort | Hugging Face → |
Sizes from the Hugging Face file listing, read 2026-09-25. “Needed” = file + 4 GB working memory for this model + 0.8 GB kept free for the system.
03The text encoder
UMT5-XXL + wav2vec2: 11.4 GB as 16-bit, 6.7 GB as FP8, 3.7 GB as GGUF Q4_K_M (plus the wav2vec2 audio encoder (0.6 GB)). ComfyUI encodes the prompt first and can push the encoder out of VRAM before sampling, so it does not have to fit together with the model. On 16 GB the FP8 encoder fits on its own, so prompt encoding stays fast.
04About this GPU
The RTX 4080 Super 16 GB is an Ada Lovelace GPU with hardware FP8, so ComfyUI can compute Comfy-Org's FP8 files natively: small and fast. (Plain FP8 files use FP8 maths with the --fast fp8_matrix_mult option.)
RTX 4080 Super 16 GB: 16 GB GDDR6X · 256-bit · 736 GB/s · Ada Lovelace. Everything that runs on the RTX 4080 Super 16 GB →
05What more VRAM would change
With 24 GB you could run Wan 2.2 S2V at 8-bit or better (FP8, 16.4 GB) with no offloading: for example on the RTX 4090 24 GB, RTX 3090 24 GB, RX 7900 XTX 24 GB.
What changes from the RTX 4080 Super 16 GB to the RTX 5090 32 GB →
06Measured and reported results
Nobody has sent measured numbers for this pair yet. If you run Wan 2.2 S2V on a RTX 4080 Super 16 GB, send your time per image and peak VRAM and it will appear here, credited.
07Questions
How much VRAM does Wan 2.2 S2V need?
Around 14.3 GB with the smallest file (Q2_K) and 21.2 GB with an 8-bit file (FP8), counting working memory and a small system reserve. The full 16-bit file needs about 37.4 GB.
Which Wan 2.2 S2V file should I download for the RTX 4080 Super 16 GB?
Q2_K (9.5 GB) from QuantStack/Wan2.2-S2V-14B-GGUF. Load it with Unet Loader (GGUF) from the ComfyUI-GGUF node pack.
Is FP8 faster than GGUF on the RTX 4080 Super 16 GB?
It can be. This GPU has FP8 hardware, and ComfyUI computes FP8 natively for files made for it (Comfy-Org's fp8_scaled files), or for any FP8 file with the --fast fp8_matrix_mult option. GGUF files are unpacked on the fly, which costs some speed.
How much do I need to download for Wan 2.2 S2V on the RTX 4080 Super 16 GB?
About 17.1 GB for the model file, text encoder and VAE listed on this page, and the same again free on disk. With a 16 GB card, 32 GB of system RAM or more is recommended.