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Can the RTX 3080 10 GB run LTX-2.5 (22B)?

Not entirely. Even Q4_K_M is 9.9 GB over 10 GB, so ComfyUI keeps part of it in system RAM.

Video model · 22B10 GB GDDR6X · 320-bit · 760 GB/s · AmpereData 2026-10-01
Offload
Not entirely in VRAM, but it can still run.

The smallest sensible file, Q4_K_M (15.1 GB), needs about 19.9 GB - 9.9 GB more than RTX 3080 10 GB has. ComfyUI can still run it by streaming part of the model from system RAM. How much slower that is depends on your ComfyUI version, the file format and the PCIe link - see the note below.

Best fileQ4_K_M
File size15.1 GB
VRAM needed~19.9 GB
System RAM48 GB+
Memory map · RTX 3080 10 GB19.9 GB needed · 9.9 GB over 10 GB
010 GB20 GB
Weights Q4_K_M · 15.1 GBWorking memory · 4.0 GBReserve · 0.8 GBSpills to system RAM · 9.9 GB

01With more VRAM

With 32 GB you could run LTX-2.5 at 8-bit or better (Q8_0, 23.6 GB) with no offloading: for example on the RTX 5090 32 GB.

What changes from the RTX 3080 10 GB to the RTX 3090 24 GB → · What changes from the RTX 3080 10 GB to the RTX 5070 Ti 16 GB →

02Every LTX-2.5 file on 10 GB

FileSizeNeededOn this cardQualityDownload
16-bit
SAFETENSORS · Lightricks
42.0 GB46.8 GB36.8 GB too bigthe original weightsHugging Face →
Q8_0
GGUF · realrebelai
23.6 GB28.4 GB18.4 GB too bigpractically identical to the originalHugging Face →
Q6_K
GGUF · realrebelai
18.7 GB23.5 GB13.5 GB too bigvery close to the originalHugging Face →
Q5_K_M
GGUF · realrebelai
16.8 GB21.6 GB11.6 GB too bigclose; small differences in fine detailHugging Face →
Q4_K_M ←
GGUF · realrebelai
15.1 GB19.9 GB9.9 GB too biggood; some loss in fine detail and textHugging Face →
Q3_K_M
GGUF · realrebelai
11.5 GB16.3 GB6.3 GB too bignoticeable loss of detailHugging Face →
Q2_K
GGUF · realrebelai
8.8 GB13.6 GB3.6 GB too bigheavy loss; a last resortHugging Face →

“Needed” adds 4 GB of working memory for LTX-2.5 and a 0.8 GB reserve. Sizes 2026-10-01.

03What to download

PartFileFolderSize
ModelLTX-2.5-Distilled-Q4_K_M.gguf
Q4_K_M · realrebelai/LTX-2.5_GGUFs
models/unet15.1 GBDownload →
Text encodergemma4-12b-with-proj-ltx-2.5-comfy-int8-convrot.safetensors
Gemma 4 12B + LTX projection INT8 (convrot) · Lightricks/LTX-2.5
models/text_encoders15.4 GBDownload →
VAEltx-2.5-video-vae-bf16.safetensors
LTX-2.5 video VAE (DiffVAE) BF16 · Lightricks/LTX-2.5
models/vae1.5 GBDownload →
Also neededltx-2.5-audio-vae-bf16.safetensors
LTX-2.5 audio VAE + vocoder BF16 · Lightricks/LTX-2.5
models/vae0.4 GBDownload →
Total download · keep about the same free on disk32.3 GB

Alternatives: Gemma 4 12B + LTX projection BF16 (26.3 GB). Only for some workflows: LTX-2.5 latent spatial upscaler x2 (1.0 GB, official two-stage template); Gemma 4 E2B INT8 (prompt enhancer, optional) (5.2 GB, only if prompt enhancer enabled). Sizes from Hugging Face, 2026-10-01.

System RAM: 48 GB or more. These files take about 32.3 GB of RAM while loaded, 38.3 GB with Windows and ComfyUI. What happens with less. calculated

04The text encoder

At 15.4 GB even the smallest Gemma 4 12B (custom LTX-2.5 build) file is too big for 10 GB, so it runs from system RAM. That slows down reading the prompt, not the picture. Sizes: 16-bit 26.3 GB, INT8 15.4 GB. Why the encoder does not count against VRAM →

05Measured and reported results

Nobody has sent measured numbers for this pair yet. If you run LTX-2.5 on a RTX 3080 10 GB, send your time per image and peak VRAM and it will appear here, credited.

06About the RTX 3080 10 GB

The RTX 3080 10 GB (Ampere) has no FP8 compute. FP8 files still load and save memory, but ComfyUI converts them back before the maths, so there is no speed gain - Q8_0 GGUF is the closer-to-original 8-bit choice. ComfyUI can compute INT8 files natively on NVIDIA, which is worth a try where a model offers one.

10 GB GDDR6X · 320-bit · 760 GB/s · Ampere. Everything that runs on it →

07Questions

How much VRAM does LTX-2.5 need?

Around 13.6 GB with the smallest file (Q2_K) and 28.4 GB with an 8-bit file (Q8_0). The full 16-bit file needs about 46.8 GB.

Which LTX-2.5 file should I download for the RTX 3080 10 GB?

Q4_K_M (15.1 GB) from realrebelai/LTX-2.5_GGUFs. Load it with Unet Loader (GGUF) from the ComfyUI-GGUF node pack.

How much do I need to download for LTX-2.5 on the RTX 3080 10 GB?

32.3 GB: LTX-2.5-Distilled-Q4_K_M.gguf, gemma4-12b-with-proj-ltx-2.5-comfy-int8-convrot.safetensors, ltx-2.5-video-vae-bf16.safetensors, ltx-2.5-audio-vae-bf16.safetensors.